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The Effects of Opioid Taper on Opioid-Induced Hyperalgesia

NCT03063905 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2018-03-21

No results posted yet for this study

Summary

Evidence to support the effectiveness of ongoing opioid therapy for the treatment of chronic non-malignant pain is lacking. In fact, data suggest that patient outcomes improve when tapered off opioid analgesics. To better understand the role opioid therapy plays in the experience of pain, we will study measured pain sensitivity in opioid dependent patients over the course of and 3 months following a standardized opioid taper. By isolating the effect of opioid taper in patients without pain, preliminary evidence of effect size can be used to guide clinicians treating patients with chronic pain.

Conditions

  • Buprenorphine
  • Pain

Interventions

DRUG

Buprenorphine

Patients taking buprenorphine to wean off an opiate addiction

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH

  • Georgetown University

    lead OTHER

Principal Investigators

  • Peggy Compton, RN, PhD · Georgetown University

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-01-31
Primary Completion
2018-02-28
Completion
2018-02-28

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03063905 on ClinicalTrials.gov