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MTHFR Mutation and Concentration of B12,Folic Acid,Homocysteine and HS CRP in the Blood of Pregnant Women With GDM.

NCT04952324 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2023-04-19

No results posted yet for this study

Summary

Research hypothesis:

* pregnant women with gestational diabetes have elevated serum CRP values and homocysteine compared to pregnant women with normal glucose metabolism
* Elevated CRP and homocysteine values are associated with poorer perinatal outcome.
* reduced concentrations of folic acid and vitamin B 12 are associated with higher homocitein values
* Carriers of the MTHFR gene mutation have higher homocysteine concentrations

Conditions

  • Gestational Diabetes

Interventions

OTHER

Blood sampling and determination of MTHFR mutation,vitamin B12, folic acid, homocystein and HS CRP

Periferal Blood sampling and determination of MTHFR mutation,vitamin B12, folic acid, homocystein and high sensitive CRP

Sponsors & Collaborators

  • University of Mostar

    lead OTHER

Principal Investigators

  • Vajdana Tomic, prof. dr · Faculty of Health Studies, Mostar

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-09-01
Primary Completion
2022-12-31
Completion
2022-12-31

Countries

  • Bosnia and Herzegovina

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04952324 on ClinicalTrials.gov