Associations of Combinations of Single-nucleotide Polymorphisms in Women With Premature Ovarian Failure
NCT04943354 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 238
Last updated 2024-03-12
Summary
Research objective.
\- To study the associations between combinations of single nucleotide polymorphisms and behavioural risk factors with non-communicable diseases and adverse outcomes in women with premature ovarian failure.
Research objectives:
* To study the associations between combinations of single-nucleotide polymorphisms and behavioural risk factors with heart rate disorders and adverse outcomes in women with premature ovarian failure
* Examine the associations between combinations of single nucleotide polymorphisms and behavioural risk factors with stable STIs in women with premature ovarian failure.
* Examine the associations between combinations of single nucleotide polymorphisms and behavioural risk factors with thrombomolia in women with premature ovarian failure
* Study the associations between combinations of single nucleotide polymorphisms and behavioural risk factors and adverse cardiovascular outcomes in women with premature ovarian failure.
Conditions
- Primary Ovarian Insufficiency
- Cardiovascular Diseases
- Menopause, Premature
- Coronary Disease
- Pulmonary Embolism
- Arrhythmias, Cardiac
- Polymorphism, Single Nucleotide
Interventions
- BEHAVIORAL
-
Taking a person's venous blood
Collection of 5 ml of the patient's venous blood, carried out according to standard rules.
Sponsors & Collaborators
-
Ryazan State Medical University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- DIAGNOSTIC
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Max Age
- 45 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-09-01
- Primary Completion
- 2022-06-03
- Completion
- 2023-12-12
Countries
- Russia
Study Locations
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