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Soluble Factors and Renal Outcome in Preeclampsia

NCT04940260 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 42

Last updated 2021-06-29

No results posted yet for this study

Summary

Preeclampsia (PE) is an important complication of pregnancy and can lead to chronic kidney disease by causing endothelial damage and podocyte loss, Soluble forms-like tyrosine kinase-1 (sFlt-1), placental growth factor (PlGF), sFlt1 / PlGF ratio and endoglin are the biomarkers for the differential diagnosis of preeclampsia and other diseases. We aim to explore the correlation of these biomarkers with long term renal function, blood pressure and urine albumin creatinine ratio (UACR) in PE patients.

Conditions

Interventions

DIAGNOSTIC_TEST

Renal function

measure eGFR at one year post partum

DIAGNOSTIC_TEST

proteinuria

measure urine protein creatinine ratio at one year postpartum

Sponsors & Collaborators

  • Bangkok Metropolitan Administration Medical College and Vajira Hospital

    lead OTHER_GOV

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-10-01
Primary Completion
2020-12-15
Completion
2021-01-31

Countries

  • Thailand

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04940260 on ClinicalTrials.gov