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Kidney Injury Biomarkers in Preeclampsia

NCT03217916 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2017-07-14

No results posted yet for this study

Summary

we found different pattern of podocyte glycoproteins and kidney injury biomarkers in urine specimens between preeclampsia and pregnancy complicated with chronic hypertention compared with normotensive pregnant controls.abnormally elevayed urine biomarkers in severe preeclampsia were completely or prtially reduced 6-8 weaks after delivery to levels comparable with those of normal pregnant subjects.

Conditions

  • Hypertension, Pregnancy-Induced

Interventions

DIAGNOSTIC_TEST

Elisa assay of podocyte glycoprotein in urine

Biomarkers evaluated in urine specimens including podocyte glycoproteins nephrin and podocalyxin, All biomarkers were measured by ELISA. Assay information for sources of ELISA kits, standard cure range, sample dilution factors, etc. All assays will be performed following the manufacture's instructions. All specimens will be measured in duplicate. Personnel who performed the assays of analyteswere blinded to the clinical information.

Sponsors & Collaborators

  • Luxor International Hospital

    collaborator UNKNOWN

  • Woman's Health University Hospital, Egypt

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-08-01
Primary Completion
2018-02-01
Completion
2018-03-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03217916 on ClinicalTrials.gov