Impact of Obesity on Post-operative Cognitive Dysfunction: Role of Adipose Tissue
NCT04907565 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 115
Last updated 2026-03-09
Summary
This research aims at describing the relationship between white adipose tissue inflammation and post-operative cognitive dysfunctions.The possible link between inflammatory cytokines secretions of the white adipose tissue of a surgical wound and the arising of patient's cognitive dysfunction in the post-operative course will be investigated. The hypothesis is that obese patient's inflammation of the white adipose tissue leads to cognitive dysfunction.
Conditions
- Obesity
- Cognitive Impairment
- Post-Operative Confusion
Interventions
- BIOLOGICAL
-
Blood sampling
4 tubes of 7 mL of blood will be collected
- BIOLOGICAL
-
white adipose tissue sampling
At the beginning of the surgery, samples of white adipose tissue from the surgical wound will be collected.
Sponsors & Collaborators
-
University Hospital, Toulouse
lead OTHER
Principal Investigators
-
François Labaste, MD, PhD · University Hospital, Toulouse
Eligibility
- Min Age
- 60 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-09-21
- Primary Completion
- 2024-09-30
- Completion
- 2025-03-30
Countries
- France
Study Locations
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