Improving the Accuracy of Referrals of Patients With Chest Pain

Summary

This is a multicenter, prospective, investigator-initiated, randomized controlled trial aiming to reduce the percentage of non-cardiac chest pain (NCCP) patients admitted to the cardiac emergency department (ED) by performing the modified HEART score by emergency medical transport (EMT) personnel.

Conditions

• Chest Pain
• Acute Coronary Syndrome
• Myocardial Infarction
• Myocardial Ischemia
• Heart Attack

Interventions

DIAGNOSTIC_TEST

modified HEART score (including POC hs cTnI analysis)

The modified HEART score was developed in 2007 and has been validated to stratify the risk of short-term adverse cardiac events in patients with chest pain at the ED. Negative predictive value (NPV) of the modified HEART score for ACS as well as positive predictive value (PPV) for major adverse cardiac events (MACE) within 6 weeks after presentation is high. The modified HEART score is an acronym for history, ECG, age, risk factors and troponin at arrival.The components can be rated 0,1 or 2 points each and result in a total score between 0 and 10.

OTHER

Standard care and triage according to the local (EMT)protocol.

Standard care and triage of chest pain patients according to the local (EMT)protocol.

Sponsors & Collaborators

• Siemens Healthineers Nederland B.V.

  collaborator UNKNOWN

• VieCuri Medical Centre

  lead OTHER

Principal Investigators

• Braim Rahel, Dr. · Viecuri Medical Centre Northern Limburg

• Joan Meeder, Dr. · Viecuri Medical Centre Northern Limburg

• Cees de Vos, Dr. · Laurentius Hospital Roermond

• Arnoud van 't Hof, Prof. dr. · Zuyderland MC

• Robert Willemsen, Dr. · General practitioner office Nazareth Maastricht

Study Design

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2021-07-04

Primary Completion

2023-06-01

Completion

2024-06-01

Countries

• Netherlands

Study Locations