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Hyaluronic Acid in Counteracting Aphthous Stomatitis

NCT04884464 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 49

Last updated 2021-07-22

No results posted yet for this study

Summary

Oral mucosal ulcers can determine a real worsening of the quality of life. Conventional therapy usually lasts not less than 2-3 weeks, and carries a high risk of serious side effects; furthermore, ulcers often recur. The use of hyaluronic acid applied as an adhesive gel over the lesions seems to have potential in terms of efficacy and the avoidance of side effects. Of course, hyaluronic acid-based formulations show different effects and tolerability. In this retrospective observational study, the results obtained using a hyaluronic-acid based medical device applied for 14 days to counteract ulcers in adults will be reported.

Conditions

  • Aphthous Stomatitis

Interventions

DEVICE

Hyaluronic acid-based gel

Dosage: application of an even coat of 1mm thickness Frequency: 3 times/day (after main meals) Duration: 2 weeks

DRUG

Chlorhexidine Gluconate

Dosage: application of an even coat of 1mm thickness Frequency: 3 times/day (after main meals) Duration: 2 weeks

Sponsors & Collaborators

  • University of Urbino "Carlo Bo"

    lead OTHER

Principal Investigators

  • Davide Sisti, PhD · University of Urbino "Carlo Bo"

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-09-01
Primary Completion
2019-06-30
Completion
2019-06-30

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04884464 on ClinicalTrials.gov