MedTrace Logo

Effect of St. John's Wort in the Treatment of Recurrent Aphthous Stomatitis

NCT06839313 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 75

Last updated 2025-02-25

No results posted yet for this study

Summary

The aim of the treatment of Recurrent Aphthous Stomatitis (RAS) is to accelerate the healing of ulcers by reducing pain and inflammation, thus enabling patients to perform their oral functions comfortably. It has been said many times in the literature that St. John's wort is very effective in wound healing.In this study, the evaluation of the therapeutic effects of St. John's wort extract on the clinical symptoms and ulcer healing rate in patients with Recurrent Aphthous Stomatitis (RAS), a condition with no definitive treatment, was aimed.

Conditions

  • Stomatitis, Aphthous

Interventions

DRUG

Kenacort A Orabase® pomad , Bristol-Myers Squibb İlaçları Inc. İstanbul , Türkiye

Apply to the injured area 4 times a day

COMBINATION_PRODUCT

Hyaluronic acid, Aftamed ® Oral jel , AktiFarma . İstanbul, Türkiye

Apply to the injured area 4 times a day

COMBINATION_PRODUCT

St. John's wort oil, Zade Vital; Health&Fitness, Developed With Ege Üniversiesi Argefar

Apply to the injured area 4 times a day

Sponsors & Collaborators

  • Batman University

    lead OTHER

Principal Investigators

  • Rojdan F GÜNEŞ UYSAL, PhD · Batman University

  • Giray G TEKİN, PhD · Batman University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-02-01
Primary Completion
2025-03-31
Completion
2025-04-15

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06839313 on ClinicalTrials.gov