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Vitamin D Oral Gel for Prevention of Radiation Induced Oral Mucositis

NCT04308161 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2020-03-13

No results posted yet for this study

Summary

The main aim of this study was to evaluate clinically the effect of topical oral vitamin D gel in comparison to conventional therapy in prevention of radiation - induced oral mucositis

Conditions

  • Oral Mucositis Due to Radiation

Interventions

DRUG

vitamin D oral gel

vitamin D is a fat soluble vitamin which has important calcemic roles in the body regarding bone homeostasis and calcium/phosphorus balance. Recently, the non-calcemic roles of vitamin D as anti-inflammatory, anti-oxidant and immuno-regulatory functions have been widely reported.So, we tried to use it for prevention of radiation induced oral mucositis

DRUG

Miconazole Topical Gel

topical anti fungal agent

DRUG

BBC oral spray

Topical anesthetics and anti-inflammatory agent

DRUG

Oracure gel

Topical analgesic gel

OTHER

Alkamisr sachets

Sodium bicarbonate mouthwash

Sponsors & Collaborators

  • Hams Hamed Abdelrahman

    lead OTHER

Principal Investigators

  • Islam s Bakr, BDS · Alexandria University

  • azza m zaki, Phd · Alexandria University

  • Riham m El-Moslemany, Phd · Alexandria University

  • Rasha o Elsaka, Phd · Alexandria University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
25 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-11-02
Primary Completion
2020-10-31
Completion
2020-12-31

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04308161 on ClinicalTrials.gov