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Effectiveness of Topical Olive Oil in Prevention and Management of Radiation Induced Oral Mucositis

NCT05322421 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2024-08-02

No results posted yet for this study

Summary

This research aims to investigate the effectiveness of topical olive oil application both clinically and biochemically as a suitable affordable treatment modality for prevention and management of radiation oral mucositis and its associated pain for head and neck cancer patients receiving radiotherapy.

Conditions

  • Radiation Mucositis
  • Oral Mucositis (Ulcerative) Due to Radiation
  • Radiation-Induced Mucositis

Interventions

OTHER

Topical Olive Oil

Olive oil will be placed in 200 ml opaque glass containers. For each application, a new stick with a sponge will be submerged into one of the agents to absorb then coat the tongue, buccal mucosa, lips, and hard palate. Patients will be instructed to refrain form eating for 1 hour after the application

OTHER

Sodium bicarbonate 5% solution

Sodium bicarbonate 5% solution will be placed in 200 ml opaque glass containers. For each application, a new stick with a sponge will be submerged into one of the agents to absorb then coat the tongue, buccal mucosa, lips, and hard palate. Patients will be instructed to refrain form eating for 1 hour after the application

Sponsors & Collaborators

  • Salma Hesham Elhoufi

    lead OTHER

Principal Investigators

  • Suzan S Ibrahim, Professor · Ain Shams University

  • Radwa Ragheb, Lecturer · Ain Shams University

  • Salma H Elhoufi · Ain Shams University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
25 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-01-10
Primary Completion
2022-09-10
Completion
2022-12-15

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05322421 on ClinicalTrials.gov