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Improving Low ASPECTS Stroke Thrombectomy

NCT04862507 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2023-05-24

No results posted yet for this study

Summary

Improving Low ASPECTS Stroke Thromectomy (I-LAST) is an academic, independent, prospective, multicenter, observational registry study. Consecutive patients treated with endovascular stroke treatment will be enrolled in German stroke centers. Patients receive regular care and data will be collected as part of clinical routine. Baseline clinical and procedural information as well clinical follow-up information during in-hospital stay, and up to 90 days of stroke onset are collected. Data collected include demographics, National Institute of Health Stroke Scale (NIHSS) on admission, pre-treatment ASPECTS, information on timing and success of interventional treatment, procedural complications, intracranial hemorrhage, and functional outcome. Advanced imaging biomarkers will be tested and validated aiming to improve treatment selection and outcome prediction of patients presenting with extensive baseline infarction.

Conditions

  • Acute Ischemic Stroke

Interventions

OTHER

Telephone call on day 90

telephone call on day 90 to assess the primary outcome (mRs 90)

DIAGNOSTIC_TEST

Quantification of lesion water uptake by CT densitometry

Retrospective quantification of lesion water uptake by CT densitometry in admission and follow-up imaging

Sponsors & Collaborators

  • University of Kaiserslautern

    collaborator OTHER

  • University Hospital Muenster

    collaborator OTHER

  • University of Rostock

    collaborator OTHER

  • University Hospital, Basel, Switzerland

    collaborator OTHER

  • Charite University, Berlin, Germany

    collaborator OTHER

  • Klinikum Bremen-Mitte, gGmbH

    collaborator OTHER

  • Universitätsklinikum Hamburg-Eppendorf

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-01
Primary Completion
2027-01-01
Completion
2028-01-01

Countries

  • Germany
  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04862507 on ClinicalTrials.gov