MedTrace Logo

Hypoperfusion-hypodensity Mismatch for the Identification of Patients With Stroke Within 4.5 Hours

NCT04277728 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 689

Last updated 2020-02-20

No results posted yet for this study

Summary

Intravenous thrombolysis is recommended within 4.5 hours of stroke onset. The aim of the study is to evaluate whether a hypodensity on native CT within the virtually entire area of hypoperfusion on perfusion CT, i.e. hypoperfusion-hypodensity mismatch, identifies patients within the time window of thrombolysis in a multicenter cohort. The investigators hypothesize hypoperfusion-hypodensity mismatch will identify patients ≤ 4,5 hours of symptom onset with \>70% specificity and \>85% positive predictive value.

Conditions

  • Acute Ischemic Stroke

Interventions

DIAGNOSTIC_TEST

hypoperfusion-hypodensity mismatch

hypoperfusion-hypodensity mismatch on computed tomography

Sponsors & Collaborators

  • University Hospital Muenster

    lead OTHER

Principal Investigators

  • Jens Minnerup, MD · University Hospital Muenster

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-01-01
Primary Completion
2019-12-31
Completion
2019-12-31

Countries

  • Germany

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04277728 on ClinicalTrials.gov