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Mechanical Complications of Acute Myocardial Infarction During COVID-19 Pandemics

NCT04813692 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 130

Last updated 2023-06-12

No results posted yet for this study

Summary

The ongoing COVID-19 pandemics has put an overwhelming pressure on the healthcare systems of many European countries. Such a situation has potentially led to delayed and impaired access to appropriate treatment for patients affected by other severe, non-COVID-19-related conditions, including cardiovascular diseases. This resulted in a reported lower admission, but higher mortality rate for AMI patients.

Such a situation might be explained by many factors, including unavailability of early reperfusion therapy and late hospital presentation of AMI patients due to a general anxiety related to the COVID-19 contagious risk of the hospital environment. As a matter of fact, during this year of pandemics, several case reports suggested a new, significant surge of post-AMI mechanical complications, sometimes describing patients admitted in too severe conditions to consider surgical repair a viable option, and therefore inevitably undergone an unfavorable outcome.

Therefore, we decided to involve the large network of European centers already participating to the "Caution Study 1", in order to study the impact of COVID-19 pandemics on the outcomes, incidence and treatments of post-AMI mechanical complications.

Conditions

  • Ventricular Septal Rupture
  • Papillary Muscle Rupture
  • Free Wall Rupture, Heart

Interventions

PROCEDURE

Surgical repair

Surgical repair of post-infarction LVFWR or VSR

PROCEDURE

Percutaneous treatment

Percutaneous closure of post-infarction VSR (or treatment for LVFWR)

PROCEDURE

Mitral valve surgery

Mitral valve repair or replacement for post-infarction PMR

Sponsors & Collaborators

  • Maastricht University Medical Center

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-03-01
Primary Completion
2021-09-30
Completion
2022-07-31

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04813692 on ClinicalTrials.gov