Pathogenicity of B and CD4 T Cell Subsets in Multiple Sclerosis

NCT04798651 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2026-02-03

No results posted yet for this study

Summary

The study aims at identifying the type of B and CD4 T cell subsets with pathogenic properties in the different clinical forms of multiple sclerosis. This research might open new therapeutic approaches for the treatment of multiple sclerosis particularly progressive MS.

Conditions

Interventions

BIOLOGICAL

blood sample

28 ml whole blood for Peripheral blood mononuclear cell (PBMC) and monocytes isolation

BIOLOGICAL

cerebro-spinal fluid

1 ml of cerebro-spinal fluid

Sponsors & Collaborators

  • University of Bordeaux

    collaborator OTHER
  • University Hospital, Bordeaux

    lead OTHER

Principal Investigators

  • Aurélie RUET, Prof · University Hospital, Bordeaux

  • Nathalie SCHMITT, PhD · University of Bordeaux

Study Design

Allocation
NA
Purpose
OTHER
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-09-30
Primary Completion
2026-09-30
Completion
2026-09-30

Countries

  • France

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04798651 on ClinicalTrials.gov