Pathogenicity of B and CD4 T Cell Subsets in Multiple Sclerosis
NCT04798651 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 150
Last updated 2026-02-03
Summary
The study aims at identifying the type of B and CD4 T cell subsets with pathogenic properties in the different clinical forms of multiple sclerosis. This research might open new therapeutic approaches for the treatment of multiple sclerosis particularly progressive MS.
Conditions
- Multiple Sclerosis
- Clinically Isolated Syndrome
Interventions
- BIOLOGICAL
-
blood sample
28 ml whole blood for Peripheral blood mononuclear cell (PBMC) and monocytes isolation
- BIOLOGICAL
-
cerebro-spinal fluid
1 ml of cerebro-spinal fluid
Sponsors & Collaborators
-
University of Bordeaux
collaborator OTHER -
University Hospital, Bordeaux
lead OTHER
Principal Investigators
-
Aurélie RUET, Prof · University Hospital, Bordeaux
-
Nathalie SCHMITT, PhD · University of Bordeaux
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-09-30
- Primary Completion
- 2026-09-30
- Completion
- 2026-09-30
Countries
- France
Study Locations
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