Long-term Prognosis of Emergency Aneurysmal Subarachnoid Hemorrhage

Summary

Rupture of intracranial aneurysms can lead to extensive subarachnoid hemorrhage (SAH), a potentially fatal neurological emergency with mortality rates ranging from 8 to 67%. At present, surgical clipping (SC) and endovascular coiling (EC) are two main treatments for aneurysmal subarachnoid hemorrhage (aSAH), in recent years, the improvements in surgical equipment and techniques have already greatly improved the postoperative safety of patients. However, considering individual differences between patients, some still at risk due to possible complications during hospitalization or after discharge from the hospital, it will no doubt generate a large healthcare burden.

This prospective, observational clinical trial (LongTEAM) is to improve the diagnosis and treatment effect and efficiency in this field, reducing mortality, medical costs, and medical burden, while opening up new avenues for interdisciplinary clinical practice and scientific research exploration.

Conditions

• Aneurysmal Subarachnoid Hemorrhage

Interventions

PROCEDURE

Surgical clipping and endovascular coiling

Surgical clipping: Apply aneurysm clip to clip the ruptured aneurysm. Endovascular coiling：Also called endovascular embolization, to block blood flow into an aneurysm.Preventing blood flow into an aneurysm helps to keep it from rupturing.

Sponsors & Collaborators

• Peking University International Hospital

  collaborator OTHER

• Beijing Tiantan Hospital

  lead OTHER

Principal Investigators

• Fa Lin, MD · Beijing Tiantan Hospital

• Yuanli Zhao, MD · Beijing Tiantan Hospital

• Jizong Zhao, MD · Beijing Tiantan Hospital

• Runting Li, MD · Beijing Tiantan Hospital

• Xiaolin Chen, MD · Beijing Tiantan Hospital

• Yu Chen, MD · Beijing Tiantan Hospital

• Junlin Lu, MD · Beijing Tiantan Hospital

• Zhipeng Li, MD · Beijing Tiantan Hospital

• Heze Han, MD · Beijing Tiantan Hospital

• Debin Yan, MD · Beijing Tiantan Hospital

• Shuo Wang, MD · Beijing Tiantan Hospital

Eligibility

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2012-04-01

Primary Completion

2032-03-01

Completion

2032-04-01

Countries

• China

Study Locations