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Brain Aneurysms: Utility of Cisternal Urokinase Irrigation

NCT04792944 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 247

Last updated 2021-03-11

No results posted yet for this study

Summary

Despite the efforts made in its treatment, aneurysmal subarachnoid haemorrhage continues to induce high mortality and morbidity rates. Today there are treatment protocols in all hospitals. The vast majority prefer, whenever possible, the endovascular route, given its lesser aggressiveness and morbidity.

Although embolization prevents aneurysm' rebleeding, it does remove the subarachnoid blood clot. Therefore, it does not modify the evolution, incidence and severity of vasospasm.

The idea is to carry out a 10-year retrospective study classifying patients into five groups based on the type of treatment received, analyzing the results' differences. The aim is to improve what is done as much as possible and to be able to propose potential areas for improvement. Besides, this study will be the basis of a future prospective study, prepared without the current one's biases and errors.

Conditions

  • Subarachnoid Hemorrhage, Aneurysmal
  • Vasospasm, Cerebral
  • Hydrocephalus

Interventions

DRUG

Urokinase

Washing the subarachnoid clot induced by a subarachnoid haemorrhage aneurysmal bleeding with urokinase after aneurysm clipping

PROCEDURE

Endovascular treatment

Aneurysm treatment through endovascular methods

PROCEDURE

Clipping

Surgical clipping of brain aneurysms

PROCEDURE

External ventricular drain

Insertion of an external ventricular drain to treat acute hydrocephalus

Sponsors & Collaborators

  • University of Valencia

    lead OTHER

Principal Investigators

  • Teresa V Moratal, Nurse · Hospital General Universitario Valencia

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-01-01
Primary Completion
2020-12-31
Completion
2020-12-31

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04792944 on ClinicalTrials.gov