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Impact of Age and Geriatric Co-morbidities on Lymphocyte Phenotype in Patients 70 Years of Age and Older

NCT04772092 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2022-09-08

No results posted yet for this study

Summary

An individual's immune profile changes with age, and can sometimes be involved in the development of certain diseases such as infections or cancers, in a process called immunosenescence. Some data tend to show that there is a link between this immune profile and geriatric fragility (autonomy, difficulties with walking, memory, undernutrition, co-morbidities, depression). The aim of this study is to describe this profile, or immune phenotype, and to see if there is a link with the different aspects of geriatric assessment in patients without cancer or infection. In addition, these data will serve as a basis for comparison with the same analyses performed on breast cancer patients at the Centre Georges François Leclerc.

Conditions

  • Geriatrics Immunosenescence

Interventions

BIOLOGICAL

Blood samples

during the routine blood test, collection of additional blood samples: * 1 x 5 mL heparinized tube for plasma collection and storage * 1 heparinized 5 mL tube for immunophenotyping * 4 x 10 mL EDTA tubes for white blood cell (WBC) collection and cryopreservation

OTHER

Data collection

* clinical examination data * test results to measure the degree of geriatric fatigability * Frailty screening questionnaire for neoplasia patients (G8 score)

Sponsors & Collaborators

  • Centre Hospitalier Universitaire Dijon

    lead OTHER

Eligibility

Min Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-11-30
Primary Completion
2021-11-30
Completion
2021-11-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04772092 on ClinicalTrials.gov