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Reduction the Duration of Antibiotic Therapy in the Elderly (PROPAGE)

NCT02173613 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 117

Last updated 2022-05-02

No results posted yet for this study

Summary

The main objective is to evaluate the interest of the repeated measurement of procalcitonin in patients with pulmonary infection to reduce the duration of antibiotic therapy in comparison with a conventional clinical strategy.

Conditions

  • Lung Infection

Interventions

OTHER

procalcitonine

The recommendations will be based on the level of PCT: 4 levels of advice will be given: * It is highly recommended to stop antibiotics if PCT \<0.1ng/ml, and the recommended stop if 0.1ng/ml \<PCT \<0.25 ng / ml. * It is recommended to continue treatment if 0.25 ng / ml \<PCT ng / ml. * Finally, if the initial PCT greater than 10 ng / ml, a stop will be advised in case of reduction to less than 10% of baseline level.

Sponsors & Collaborators

  • University Hospital, Grenoble

    lead OTHER

Principal Investigators

  • Gaetan Gavazzi · University Clinic of Geriatrics Medicine, Division of Medicine multidisciplinary CHU de Grenoble,

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-08-31
Primary Completion
2015-12-31
Completion
2016-03-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02173613 on ClinicalTrials.gov