Comparison of the Frequency of Subclinic Synovitis in the Distal Interphalangeal Joints of the Hand in Psoriasis Patients
NCT04750993 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 56
Last updated 2021-02-11
Summary
In this cross-sectional study, it was planned to compare the frequency of subclinical synovitis in the distal interphalangeal joints of the hands in psoriasis patients. 28 patients followed up by the Dermatology Department with a diagnosis of psoriasis and referred to us and 28 healthy volunteers were included in the study. Participants' age, gender, body mass index (BMI), year of psoriasis diagnosis, treatments they received, and comorbid diseases were recorded as demographic information. Psoriasis Area and Severity Index (PASI) and Nail Psoriasis Severity Index (NAPSI) were calculated by a dermatologist.
Tenderness in the distal interphalangeal joints of both hands was evaluated by palpation.
Subsequently, the presence of ultrasonographic synovitis findings of the participants was examined by a physician who was experienced in musculoskeletal ultrasonography and was blind to clinical evaluations. Scoring was done with the EULAR GS / PD joint scoring system and EULAR-OMERACT composite scoring system. The scores of the most affected joint were used in statistical analysis. Comparisons were made between psoriasis and control groups in terms of scores. Relationships between variables in the psoriasis group were examined.
Conditions
- Psoriasis
- Synovitis
Interventions
- DIAGNOSTIC_TEST
-
musculoskeletal ultrasonography
The presence of subclinic synovitis findings in the hand joints was evaluated with musculoskeletal ultrasonography.
Sponsors & Collaborators
-
Ufuk University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-10-01
- Primary Completion
- 2015-06-01
- Completion
- 2015-06-01
Countries
- Turkey (Türkiye)
Study Locations
More Related Trials
-
Enthesitis Assessment Before and After Anti-Tumor Necrosis Factor Treatment in Spondyloarthritis
NCT04953871 ·Status: COMPLETED ·Phase: PHASE4
-
Study of Power Doppler Ultrasound (PDUS) to Measure Response of Secukinumab Treatment in Patients With Active Psoriatic Arthritis (PsA)
NCT02662985 ·Status: COMPLETED ·Phase: PHASE3
-
Prevelance of Axial Spondylosis Arthritis in Inflammatory Bowel Disease and Its RESPONSE to Tumour Necrosis Factor (TNF) Inhibitors Treatment in Assiut University Hospital
NCT06601595 ·Status: NOT_YET_RECRUITING
-
Biomarker Signature and Musculoskeletal Ultrasound Profile in Rheumatoid Arthritis Patients
NCT02476084 ·Status: COMPLETED
-
Does Immunogenicity Have an Influence on the Efficacy of Anti-TNF Therapy in Patients With AS: An Inception Cohort Study
NCT02687620 ·Status: UNKNOWN
-
Rheumatoid Arthritis Patients on Adalimumab to Evaluate Its Effect on Synovitis Using Ultrasonography in an Egyptian Population
NCT01782469 ·Status: TERMINATED
-
Study to Evaluate the Efficacy of Adalimumab in Patients With Erosive Osteoarthritis of the Interphalangeal Finger Joints
NCT00296894 ·Status: COMPLETED ·Phase: PHASE2
-
Immune-Competent Cell Manifestations in Psoriatic Arthritis Achilles Tendons
NCT03248284 ·Status: RECRUITING
-
Ultrasound and Withdrawal of Biological DMARDs in Rheumatoid Arthritis
NCT01602302 ·Status: TERMINATED ·Phase: PHASE4
-
Prognostic Indicators and Determinants of the 2-5 Year Outcome in a Cohort of Early Synovitis Patients
NCT00001679 ·Status: COMPLETED
-
Sensitivity of Echography in Arthritis
NCT00444691 ·Status: UNKNOWN ·Phase: NA
-
A Rheumatoid Arthritis Study to Assess Early Response to Abatacept+MTX as Defined by Improvement of Synovitis Measures by Power Doppler Ultrasonography
NCT00767325 ·Status: COMPLETED ·Phase: PHASE3
-
TNF and IL23 Blocking Agents Gene Expression Ratios in the Psoriatic Arthritis Synovium_(TIGERS) Study
NCT04261010 ·Status: COMPLETED ·Phase: NA
-
To Investigate Genetic Factors Associated With the Response to Anti-TNF Therapy in Patients With Early AS
NCT02311842 ·Status: COMPLETED
-
Study Evaluating Etanercept on Skin and Joint Disease in Psoriatic Arthritis
NCT00245960 ·Status: COMPLETED ·Phase: PHASE4
-
Synovitis and Therapy Response in Inflammatory Arthritis With Contrast Enhanced Ultrasound
NCT02902562 ·Status: COMPLETED ·Phase: NA
-
Evolution of Intestinal Microbiota in Patients With Juvenile Spondylarthropathy According to Typology of Treatment
NCT04540432 ·Status: RECRUITING ·Phase: NA
-
Indications and Interest of US-guided Synovial Biopsies Performed in Clinical Practice
NCT03417167 ·Status: COMPLETED
-
Tumor Necrosis Factors (TNF)-α Blockade for Psoriatic Arthritis
NCT00432406 ·Status: COMPLETED ·Phase: PHASE4
-
Leflunomide Versus Sulfasalazine/Methotrexate in Rheumatoid Arthritis:an Ultrasound/Magnetic Resonance Imaging Study
NCT01659242 ·Status: TERMINATED ·Phase: PHASE4
-
Enthesitis With Ultra Sonography Doppler in Spondyloarthropathies Treated With Infliximab (Study P04440)
NCT00686894 ·Status: TERMINATED ·Phase: PHASE4
-
Etanercept (Enbrel) in Undifferentiated Spondyloarthritis
NCT01289730 ·Status: UNKNOWN ·Phase: PHASE2
-
Dose Ranging Study to Evaluate the Efficacy and Safety of SAR153191 (REGN88) in Patients With Ankylosing Spondylitis
NCT01061723 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Humira® in Patients With Psoriatic Arthritis in Normal Medical Practice
NCT01111240 ·Status: COMPLETED
-
Study Evaluating the Safety and Efficacy of Etanercept in Patients With Psoriatic Arthritis Treated by Dermatologists
NCT00293709 ·Status: COMPLETED