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The Diagnostic Ultrasound Enthesitis Tool (DUET) Study

NCT04587362 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 419

Last updated 2024-05-14

No results posted yet for this study

Summary

Psoriatic arthritis (PsA) is a type of joint disease that can lead to severe joint damage and disability within the first few years of the disease. This is why early detection and treatment of the disease is essential to prevent serious joint damage and improve long-term outcomes in these patients. However, there is currently no reliable way to tell the difference between PsA and other types of joint disease. This makes it difficult to detect PsA early. Enthesitis is an inflammation of the area where muscle tendons and ligaments attach to bones. Enthesitis is a key feature in PsA and can be easily detected using ultrasonography. The aim of this research study is to develop a system to evaluate enthesitis using ultrasonography, which can be used as an effective tool in the early detection of PsA. This will help in providing patients with early treatment to prevent further joint damage.

Conditions

Interventions

DIAGNOSTIC_TEST

Musculoskeletal Ultrasound

High quality ultrasound scanners and high-resolution transducers, will be used to scan 16 joints sites for each subject. Ultrasound had excellent spatial resolution, making it an highly efficient, non-invasive tool for the assessment on enthesitis, which is an early feature of psoriatic arthritis. It is an affordable and accessible tool that is widely used in rheumatology practice.

Sponsors & Collaborators

  • Group for Research and Assessment of Psoriasis and Psoriatic Arthritis

    collaborator NETWORK

  • Women's College Hospital

    lead OTHER

Principal Investigators

  • Lihi Eder, MD, PhD · University of Toronto

  • Sibel Z Aydin, MD · University of Ottawa

  • Gurjit S Kaeley, MD · University of Florida

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-03-17
Primary Completion
2023-02-27
Completion
2023-02-27

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04587362 on ClinicalTrials.gov