Objective Measurement With TCM Pattern for AIDDES

Summary

To explore the association with TCM pattern and TCM tongue diagnosis for Autoimmune disease and Dry eye syndrome.

Conditions

• Sjögren's Syndrome
• Systemic Lupus Erythematosus
• Dry Eye Syndrome

Interventions

DIAGNOSTIC_TEST

Traditional Chinese Medicine pattern

Autoimmune disease (AID) as Sjögren's syndrome (SJS), Systemic lupus erythematosus (SLE) for comparing with the Dry eye syndrome (DES) and non AIDDES Healthy Controls subjects will take the Traditional Chinese Medicine pattern diagnosis.

DIAGNOSTIC_TEST

Traditional Chinese Medicine tongue diagnosis

Autoimmune disease (AID) as Sjögren's syndrome (SJS), Systemic lupus erythematosus (SLE) for comparing with the Dry eye syndrome (DES) and non AIDDES Healthy Controls subjects will take the Traditional Chinese Medicine tongue diagnosis.

DIAGNOSTIC_TEST

Heart rate variability

Autoimmune disease (AID) as Sjögren's syndrome (SJS) and Systemic lupus erythematosus (SLE) for comparing with the Dry eye syndrome (DES) subjects will take the Heart rate variability.

DIAGNOSTIC_TEST

Schirmer's test

Autoimmune disease (AID) as Sjögren's syndrome (SJS) and Systemic lupus erythematosus (SLE) for comparing with the Dry eye syndrome (DES) subjects will take the Schirmer's test.

DIAGNOSTIC_TEST

Ocular Surface Diseast Index (OSDI)

Autoimmune disease (AID) as Sjögren's syndrome (SJS) and Systemic lupus erythematosus (SLE) for comparing with the Dry eye syndrome (DES) subjects will take the Ocular Surface Diseast Index (OSDI).

DIAGNOSTIC_TEST

EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI)

Autoimmune disease (AID) as Sjögren's syndrome (SJS) and Systemic lupus erythematosus (SLE) for comparing with the Dry eye syndrome (DES) subjects will take the EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI).

DIAGNOSTIC_TEST

36-Item Short Form Survey (SF-36)

Autoimmune disease (AID) as Sjögren's syndrome (SJS) and Systemic lupus erythematosus (SLE) for comparing with the Dry eye syndrome (DES) subjects will take the 36-Item Short Form Survey (SF-36).

Sponsors & Collaborators

• Taipei Veterans General Hospital, Taiwan

  lead OTHER_GOV

Principal Investigators

• Chang Ching-Mao, M.D., Ph.D. · Taipei Veterans General Hospital, Taiwan

Eligibility

Min Age

20 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2021-02-01

Primary Completion

2022-11-30

Completion

2024-12-31

Countries

• Taiwan

Study Locations