Investigation of Fever Suspected as a Zoonosis Using Advanced Diagnostic Technologies
NCT04717622 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 500
Last updated 2021-11-01
Summary
Zoonosis including brucellosis and rickettsial infections are a major contributor to infectious morbidity in southern Israel. The Bedouins, a nomadic tribal population residing in the Negev area are notably exposed to domesticated animals including livestock, camels and companion animals, and their living conditions, especially with respect to poor sanitation in different Bedouin communities also expose them to rodents and disease vectors such as insects and arthropods. In this study, we aim to identify Bedouin patients arriving at the Soroka University Medical Center, a tertiary hospital un the Negev, with undifferentiated fever, suspected as a zoonosis.
We intend to use molecular methods to better diagnose the infectious agent using whole blood and serum samples, and when available other tissues or body fluid, and use next generation sequencing technology to deeply examine bacterial features such as virulence factors, and host pathogen interactions.
Conditions
- Brucellosis
- Zoonotic Disease
Sponsors & Collaborators
-
Ben-Gurion University of the Negev
collaborator OTHER -
Soroka University Medical Center
lead OTHER
Principal Investigators
-
Yael Yagel, MD · Senior doctor, infectious diseases
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-05-23
- Primary Completion
- 2023-09-30
- Completion
- 2024-03-31
Countries
- Israel
Study Locations
More Related Trials
-
Integrating Community Interventions to Eliminate Neglected Tropical Diseases
NCT03667079 ·Status: COMPLETED ·Phase: NA
-
Prevalence of Intestinal Parasitic Infections in Under-Five Children With Malnutrition in Sohag, Egypt
NCT06716060 ·Status: RECRUITING
-
Plasmodium and Other Parasites in Pregnant Women and Children Around Margibi and Montserrado Counties, Liberia
NCT03719599 ·Status: COMPLETED
-
Effect of Onchocerciasis Elimination Measures on the Incidence of Epilepsy in Maridi, South Sudan
NCT05750043 ·Status: COMPLETED
-
Rift Valley Fever in Kenya
NCT00287014 ·Status: COMPLETED
-
Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection
NCT00001645 ·Status: RECRUITING
-
New Tools for the Diagnosis, Prognosis and Treatment Follow-up in Chagas Disease
NCT01755377 ·Status: COMPLETED
-
Schistosomiasis in Women of Reproductive Age in Burkina Faso: Implications for Control
NCT00463632 ·Status: COMPLETED
-
Prevalence of Chagas Disease in Immigrant Patients With Conduction Abnormalities on Electrocardiogram
NCT00453700 ·Status: COMPLETED
-
Urogenital Schistosomiasis and Sexually Transmitted Infections in Madagascar
NCT00713999 ·Status: COMPLETED ·Phase: NA
-
Management of Soil-transmitted Helminthiasis and Strongyloidiasis
NCT01308268 ·Status: UNKNOWN ·Phase: NA
-
Infection Tracking in Travellers. The Project Aims to Identify Profiles of Travel-associated Illness and to Follow up on Long-term Sequelae of Arboviral Infections and Malaria
NCT04672577 ·Status: NOT_YET_RECRUITING
-
Chagas Disease Diagnostic - Inconclusive Serology
NCT00511589 ·Status: COMPLETED ·Phase: NA
-
Seroprevalence of Leptospirosis in Val Müstair, Switzerland
NCT05300425 ·Status: COMPLETED
-
Research for Elimination of Lymphatic Filariasis (ICIDR)
NCT00406627 ·Status: COMPLETED
-
Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP2 Passive Case Detection
NCT03356665 ·Status: COMPLETED ·Phase: NA
-
Prevention of Female Genital Schistosomiasis (FGS) in Rural High-endemic South Africa
NCT01154907 ·Status: UNKNOWN
-
Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP3 Post Elimination Monitoring
NCT04099628 ·Status: COMPLETED ·Phase: NA
-
Pathogenesis and Management of M. Ulcerans Disease, Buruli Ulcer
NCT02153034 ·Status: UNKNOWN
-
New Therapies and Biomarkers for Chagas Infection
NCT03981523 ·Status: COMPLETED ·Phase: PHASE2
-
Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: Early Test-of-cure
NCT03112655 ·Status: COMPLETED ·Phase: NA
-
Western Kenya Integrated COVID-19 Response
NCT04501458 ·Status: UNKNOWN ·Phase: NA
-
Etiology of Uncomplicated Fever in Children <5 in Rural Zanzibar
NCT01094431 ·Status: COMPLETED
-
Hantavirus Transmission in Households in Chile
NCT00533767 ·Status: TERMINATED
-
Impact of a Bi-annual CDTI on the Incidence of Epilepsy in an Onchocerciasis-endemic Area
NCT05749653 ·Status: COMPLETED ·Phase: NA