Investigation of Fever Suspected as a Zoonosis Using Advanced Diagnostic Technologies

NCT04717622 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2021-11-01

No results posted yet for this study

Summary

Zoonosis including brucellosis and rickettsial infections are a major contributor to infectious morbidity in southern Israel. The Bedouins, a nomadic tribal population residing in the Negev area are notably exposed to domesticated animals including livestock, camels and companion animals, and their living conditions, especially with respect to poor sanitation in different Bedouin communities also expose them to rodents and disease vectors such as insects and arthropods. In this study, we aim to identify Bedouin patients arriving at the Soroka University Medical Center, a tertiary hospital un the Negev, with undifferentiated fever, suspected as a zoonosis.

We intend to use molecular methods to better diagnose the infectious agent using whole blood and serum samples, and when available other tissues or body fluid, and use next generation sequencing technology to deeply examine bacterial features such as virulence factors, and host pathogen interactions.

Conditions

  • Brucellosis
  • Zoonotic Disease

Sponsors & Collaborators

  • Ben-Gurion University of the Negev

    collaborator OTHER
  • Soroka University Medical Center

    lead OTHER

Principal Investigators

  • Yael Yagel, MD · Senior doctor, infectious diseases

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-05-23
Primary Completion
2023-09-30
Completion
2024-03-31

Countries

  • Israel

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04717622 on ClinicalTrials.gov