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Neurodynamics of Prosocial Emotional Processing Following Serotonergic Stimulation With N,N-Dimethyltryptamine (DMT) and Harmine in Healthy Subjects

NCT04716335 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2022-10-04

No results posted yet for this study

Summary

The aim of the project is to assess brain network dynamics, self-referential information processing and prosociality and learning following the modulation of the serotonin-system by serotonergic-psychoactive compounds.

Conditions

  • Emotions
  • Mood
  • Cognitive Function 1, Social
  • Empathy

Interventions

DRUG

DMT

DMT

DRUG

Harmine

Harmine

DRUG

Placebo (Harmine)

Placebo for Harmine

DRUG

Placebo (DMT)

Placebo for DMT

Sponsors & Collaborators

  • University of Basel

    collaborator OTHER

  • Psychiatric University Hospital, Zurich

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
40 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-12-01
Primary Completion
2021-07-19
Completion
2022-01-10

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04716335 on ClinicalTrials.gov