MedTrace Logo

Does Serotonin System Stimulation Increase Pro-social Behavior? - A Comparative Pharmacological Neuroscientific Study in Healthy Humans

NCT06081179 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 122

Last updated 2025-11-19

No results posted yet for this study

Summary

The study looks into whether administering psychedelic substances that stimulate the serotonin system influences pro-social behavior when compared to administering substances that stimulate the dopamine system in healthy individuals.

Conditions

  • Healthy

Interventions

DRUG

Psilocybin

Single dose of psilocybin (15mg), orally in form of capsules

DRUG

3,4 Methylenedioxymethamphetamine

Single dose of MDMA (100mg), orally in form of capsules

DRUG

Methylphenidate

Single dose of methylphenidate (60mg), orally in form of capsules

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-10-24
Primary Completion
2025-09-22
Completion
2025-09-22

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06081179 on ClinicalTrials.gov