N-of-few Study of Pain Perception

NCT04664400 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2023-04-18

Study results available
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Summary

A behavioral study that will examine how pain perception is affected by different types of conditioning and by context, with a few participants and multiple sessions ("N-of-few" design).

Conditions

  • Healthy

Interventions

BEHAVIORAL

Symbolic conditioning

Participants will learn associations between cues and thermal stimuli with varying temperatures (low vs. high) through symbolic conditioning (no actual heat stimuli, only pictures of thermometers)

BEHAVIORAL

Conditioning

Participants will learn associations between cues and thermal stimuli with varying temperatures (low vs. high) from experience (with actual heat stimuli).

BEHAVIORAL

Instructions

Participants will learn associations between cues and thermal stimuli with varying temperatures (low vs. high) from verbal instructions.

BEHAVIORAL

Counterfactual

Thermal stimuli will be either the better outcome or the worse outcome out of two possible outcomes.

Sponsors & Collaborators

  • National Institute of Mental Health (NIMH)

    collaborator NIH
  • Trustees of Dartmouth College

    lead OTHER

Principal Investigators

  • Tor D Wager, PhD · Dartmouth College

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-22
Primary Completion
2021-05-24
Completion
2021-05-24

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04664400 on ClinicalTrials.gov