Effect of NMN Supplementation on Organ System Biology

NCT04571008 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 56

Last updated 2026-03-11

Study results available
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Summary

The goal of this proposal is to determine whether the beneficial effects of NMN on metabolic function observed in rodents applies to people.

Conditions

  • Glucose Metabolism Disorders

Interventions

OTHER

Placebo

Intervention will last at least 16 weeks in the form of two capsules.

DIETARY_SUPPLEMENT

Treatment

Intervention will last at least 16 weeks in the form of two or three NMN capsules (total of 300 or 450 mg/day).

Sponsors & Collaborators

  • United States Department of Defense

    collaborator FED
  • Washington University School of Medicine

    lead OTHER

Principal Investigators

  • Samuel Klein, MD · Washington University School of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
45 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-10-01
Primary Completion
2025-03-04
Completion
2025-03-04

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04571008 on ClinicalTrials.gov