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Comparison of Two Sedation Regimens for Awake Fiberoptic Intubation

NCT05736198 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 96

Last updated 2024-11-29

No results posted yet for this study

Summary

The purpose of this study is to examine the effects of different sedation drugs used for the awake fiberoptic intubation procedure. Benzodiazapines and narcotics (such as midazolam and fentanyl) are standard drugs used for sedation during awake fiberoptic intubation. Dexmedetomidine, midazolam, and fentanyl are approved by the Food and Drug Administration (FDA) procedural sedation. These drugs might be given to the patient regardless of their participation in the study.

In addition to midazolam and fentanyl study subjects will also receive either dexmedetomidine or a placebo (a salt solution that contains no drug). It is believed that dexmedetomidine will not slow down breathing as much as the combination of the valium-like drug and narcotic. In our study, we are trying to determine if this is the best drug for sedation during an awake fiberoptic procedure.

Conditions

  • Awake Fiberoptic Intubation
  • Difficult Airway

Interventions

DRUG

Dexmedetomidine

dexmedetomidine, midazolam, and fentanyl (titrated to effect) to facilitate intubation

Sponsors & Collaborators

  • University of Illinois at Chicago

    lead OTHER

Principal Investigators

  • David Glick, MD · Department of Anesthesiology Head

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-08-12
Primary Completion
2033-06-15
Completion
2034-03-01
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05736198 on ClinicalTrials.gov