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Advanced Techniques For Single-fraction Palliative Radiotherapy Versus Standard Multi Fraction Radiation

NCT04649125 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2026-02-06

No results posted yet for this study

Summary

The aim of the study is to determine if single fraction dose escalated palliative radiotherapy results in a prolonged duration of benefit for patients otherwise suitable for Multifraction (5-10#) palliative radiation. The primary endpointis to determine the percentage of patients who have achieved a substantial benefit from palliative radiotherapy and have not redeveloped symptoms by 12 months post treatment

Conditions

  • Palliative Radiotherapy

Interventions

RADIATION

dose escalation

single fraction dose escalation to the tumour

Sponsors & Collaborators

  • Northern Sydney and Central Coast Area Health Service

    collaborator OTHER

  • Royal North Shore Hospital

    lead OTHER

Principal Investigators

  • Thomas Eade · Northern Sydney Cancer Centre, Royal North Shore Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-05-31
Primary Completion
2026-06-30
Completion
2026-06-30

Countries

  • Australia

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04649125 on ClinicalTrials.gov