Shortened High-dose Palliative Radiotherapy for Lung Cancer
NCT06483308 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 37
Last updated 2026-04-13
Summary
The SHiP-Rt Study aims to investigate the safety and efficacy of reducing the number of RT fractions and RT duration, compared to the current standard of care (36Gy in 12 fractions over 16 days), by using shortened hypofractionated accelerated palliative radiotherapy (30Gy in 6 alternate-day fractions), aided by contemporary RT planning, verification, and delivery techniques.
Conditions
- Stage IV Lung Cancer
Interventions
- RADIATION
-
Radiotherapy
Radiotherapy using 30Gy in 6 fractions (alternate days) over 12 days.
Sponsors & Collaborators
-
University Hospitals Coventry and Warwickshire NHS Trust
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-11-27
- Primary Completion
- 2026-06-30
- Completion
- 2027-06-30
Countries
- United Kingdom
Study Locations
More Related Trials
-
Piloting the Feasibility of FLT-PET/CT Non-Small Cell Lung Cancer Managed With SBRT
NCT02456246 ·Status: COMPLETED ·Phase: NA
-
Avoiding Cardiac Toxicity in Lung Cancer Patients Treated With Curative-intent Radiotherapy
NCT03645317 ·Status: UNKNOWN ·Phase: NA
-
MR-informed Stereotactic Radiotherapy for Treatment of Ultracentral Lung Tumours Utilising a Dedicated MR-simulator for Daily Adaptation Followed by CBCT-guided Treatment Delivery
NCT06815289 ·Status: RECRUITING ·Phase: NA
-
Hypofractionated vs. Conventionally Fractionated Concurrent CRT for LD-SCLC
NCT02688036 ·Status: UNKNOWN ·Phase: PHASE3
-
Lung Stereotactic Body Radiotherapy (SBRT) Delivered Over 4 Days Versus 11 Days
NCT01620034 ·Status: COMPLETED ·Phase: NA
-
Stereotactic Body Radiation Therapy (SBRT) for Lung Tumors
NCT00632281 ·Status: COMPLETED ·Phase: NA
-
Advanced Techniques For Single-fraction Palliative Radiotherapy Versus Standard Multi Fraction Radiation
NCT04649125 ·Status: RECRUITING ·Phase: NA
-
Moderate Hypofractionated Radiotherapy for Lung Cancer
NCT03833193 ·Status: UNKNOWN ·Phase: NA
-
Palliative Steroeotactic Body Radiotherapy vs Palliative Standard Radiotherapy in Patients With Advanced Head and Neck Cancer
NCT06641791 ·Status: RECRUITING ·Phase: PHASE3
-
Safety and Tolerability of LDRT Plus Concurrent Partial SBRT and Tislelizumab in Patients With Bulky Tumors
NCT06349837 ·Status: RECRUITING ·Phase: PHASE1
-
Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer
NCT03812289 ·Status: TERMINATED ·Phase: NA
-
Phase I Study of Accelerated Hypofractionated Image-Guided Radiation Therapy
NCT03623334 ·Status: COMPLETED ·Phase: NA
-
Phase I/II Randomized Study of NBTXR3 Activated by Abscopal or RadScopal Radiation in Combination With Immunotherapy (Anti-PD-1/L-1) for Patients With Advanced Solid Malignancies
NCT05039632 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Phase 1 Study of [225Ac]-FPI-1434 Injection
NCT03746431 ·Status: TERMINATED ·Phase: PHASE1
-
Respiratory Adaptive Computed Tomography: Feasibility Study on Real-Time Gated 4DCT for Lung Cancer Radiotherapy
NCT05030207 ·Status: RECRUITING ·Phase: NA
-
WBRT With Hippocampal-avoidance Technique Followed by SRT for Extensive-stage SCLC With Baseline Brain Metastases
NCT06243003 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Stereotactic Radiotherapy With Different Fractionation Modes for the Early Lung Cancer
NCT05802641 ·Status: UNKNOWN
-
A Pilot Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) in Central Non-Small Cell Lung Cancer
NCT05138900 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Palliative Lattice Stereotactic Body Radiotherapy (SBRT)
NCT04133415 ·Status: COMPLETED ·Phase: NA
-
Spatiotemporal Stereotactic Body Radiation Therapy for the Treatment of Patients With Polymetastatic Solid Tumors
NCT05733949 ·Status: RECRUITING ·Phase: NA
-
Study Comparing Two Different Schedules of Radiation for Early-stage Lung Cancer
NCT03706027 ·Status: RECRUITING ·Phase: NA
-
A Trial to Improve Quality of Life With Stereotactic Body Radiotherapy for Patients With Painful Bone Metastases
NCT03831243 ·Status: COMPLETED ·Phase: NA
-
FLT3 Ligand Immunotherapy and Stereotactic Radiotherapy for Advanced Non-small Cell Lung Cancer
NCT02839265 ·Status: COMPLETED ·Phase: PHASE2
-
A Feasibility Study On Continuous Adaptive [18f]Fdg-Pet-Guided Radiotherapy For Head and Neck Cancer
NCT01208883 ·Status: COMPLETED ·Phase: PHASE1
-
Short Course Radiation Therapy in Palliative Treatment
NCT03196700 ·Status: COMPLETED ·Phase: NA