Endoscopic Ruler for the Assessment of Variceal Bleeding Risks (CHESS2005)

Summary

The presence of varices is a serious complication of portal hypertension in liver disease. To prevent variceal haemorrhage, screening and surveillance aims to detect high-risk varices related to varices size and determine the need for primary prophylaxis. Varices size evaluated by endoscopists might not be perfect reference, influenced by experience and machine. Endoscopic ruler is a novel tool to measure the varices size under the endoscopy. The investigators aim to evaluate the bias of varices size between endoscopists and endoscopic ruler as the reference.

Conditions

• Liver Cirrhosis
• Portal Hypertension
• Gastroesophageal Varices

Interventions

DIAGNOSTIC_TEST

Endoscopic ruler

Endoscopic ruler for varices in portal hypertension Product uses: measuring the diameter of the veins under the endoscopy for the assessment of the risk of variceal haemorrhage in patients with portal hypertension Black and white measuring rule is highly recognizable under the endoscopy The width of each cell is 1 mm, and the measuring range is 0-10 mm With smooth edge, safe and reliable

Sponsors & Collaborators

• LanZhou University

  collaborator OTHER

• Tianjin Second People's Hospital

  collaborator OTHER

• The First Affiliated Hospital with Nanjing Medical University

  collaborator OTHER

• People's Hospital of Ningxia Hui Autonomous Region

  collaborator OTHER

• The Second Affiliated Hospital of Baotou Medical College

  collaborator OTHER

• The Third Xiangya Hospital of Central South University

  collaborator OTHER

• The Second Hospital of Hebei Medical University

  collaborator OTHER

• The Affiliated Hospital Of Southwest Medical University

  collaborator OTHER

• First Hospital of China Medical University

  collaborator OTHER

• Hepatopancreatobiliary Surgery Institute of Gansu Province

  lead OTHER

Principal Investigators

• Xiaolong Qi, M.D. · LanZhou University

• Fengmei Wang, M.D. · Tianjin Second People's Hospital

• Guoxin Zhang, M.D. · The First Affiliated Hospital with Nanjing Medical University

• Shengjuan Hu, M.D. · People's Hospital of Ningxia Hui Autonomous Region

• Xianmei Meng, M.D. · The Second Affiliated Hospital of Baotou Medical College

• Xiaoyan Wang, M.D. · The Third Xiangya Hospital of Central South University

• Zhijie Feng, M.D. · The Second Hospital of Hebei Medical University

• Muhan Lv, M.D. · The Affiliated Hospital Of Southwest Medical University

• Yiling Li, M.D. · First Hospital of China Medical University

Eligibility

Min Age

18 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2020-12-23

Primary Completion

2023-04-01

Completion

2025-01-01

Countries

• China

Study Locations