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Cardiovascular and Neurovascular Regulation in GWI

NCT04586049 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 70

Last updated 2025-07-18

No results posted yet for this study

Summary

Brain blood flow regulation and autonomic dysfunction will be measured in Veterans with and without Gulf War Illness who served in the Gulf War between 1990 and 1992.

Conditions

  • Brain Blood Flow
  • Neurovascular Control

Interventions

DEVICE

MRI

Participants will undergo an MRI scan while participating in a breathing test to measure brain blood flow.

DEVICE

Transcranial Doppler Ultrasound

Participants will undergo a TCD scan while participating in a breathing test to measure brain blood flow.

OTHER

Sympathetic Nerve Activity

Participants will undergo sympathetic nerve activity testing while participating in a breathing test.

Sponsors & Collaborators

  • United States Department of Defense

    collaborator FED

  • University of Wisconsin, Madison

    lead OTHER

Principal Investigators

  • Jill N Barnes, PhD · University of Wisconsin, Madison

Eligibility

Min Age
45 Years
Max Age
68 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-05-16
Primary Completion
2026-06-30
Completion
2026-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04586049 on ClinicalTrials.gov