Camrelizumab in Combination With Apatinib in Patients With Radioactive Iodine-refractory Differentiated Thyroid Cancer
NCT04560127 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2025-07-10
Summary
This is a single arm, open-label, non-randomized and single-center phase II clinical study, to evaluate the safety, tolerance, and efficacy of Camrelizumab in combination with Apatinib in patients with Radioactive Iodine-refractory Differentiated Thyroid Cancer (RAIR-DTC).
Conditions
- Radioactive Iodine-refractory Differentiated Thyroid Cancer
Interventions
- DRUG
-
Camrelizumab combination with Apatinib
Apatinib (250mg p.o. q.d.) combined with Camrelizumab (200mg, iv, q2w)
Sponsors & Collaborators
-
Peking Union Medical College Hospital
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-09-23
- Primary Completion
- 2025-12-31
- Completion
- 2025-12-31
Countries
- China
Study Locations
More Related Trials
-
Multiple Target Kinase Inhibitor and Anti-Programmed Death-1 Antibody in Patients With Advanced Thyroid Cancer
NCT04521348 ·Status: COMPLETED ·Phase: PHASE2
-
Study of ST-1898 in Locally Advanced or Metastatic Radioiodine-Refractory Differentiated Thyroid Cancer
NCT06359847 ·Status: RECRUITING ·Phase: PHASE2
-
Study of Anlotinib in Patients With Radioiodine Refractory Differentiated Thyroid Cancer
NCT06062563 ·Status: UNKNOWN ·Phase: NA
-
A Study of Camrelizumab Plus Apatinib as Consolidation Therapy in Non-Small Cell Lung Cancer Patients Treated With Chemoradiotherapy
NCT04749394 ·Status: UNKNOWN ·Phase: PHASE2
-
Targeted or Chemotherapy Combined With Immunotherapy Versus Chemotherapy for PD-1 Inhibitor Refractory R/M NPC
NCT05549466 ·Status: UNKNOWN ·Phase: PHASE2
-
Induction Chemotherapy Combined With Immunotherapy for Locally Advanced Hypopharyngeal Carcinoma
NCT04156698 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Famitinib in Combination With Adebrelimab for the Treatment of Advanced Thyroid Cancer
NCT06146985 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Camrelizumab Combined With Apatinib in the Treatment of Advanced Sarcomatoid Carcinoma or Carcinosarcoma
NCT05265793 ·Status: UNKNOWN ·Phase: PHASE2
-
Carbon-Ion Radiotherapy Plus Camrelizumab for Locally Recurrent Nasopharyngeal Carcinoma
NCT04143984 ·Status: RECRUITING ·Phase: PHASE2
-
Induction Chemotherapy Combined With Camrelizumab in Locoregionally Advanced Hypopharyngeal Cancer
NCT04539600 ·Status: UNKNOWN ·Phase: PHASE2
-
Phase II Study of SHR-1210(Anti-PD-1 Antibody) Combination With Apatinib Versus Pemetrexed and Carboplatin in Subjects With KRAS Mutant Stage IV Non-squamous Non-small Cell Lung Cancer
NCT03777124 ·Status: TERMINATED ·Phase: PHASE2
-
PD-1 Inhibitor and Anlotinib Combined With Multimodal Radiotherapy in Recurrent or Metastatic Anaplastic Thyroid Cancer
NCT05659186 ·Status: RECRUITING ·Phase: PHASE2
-
Fluzoparib Combined With Camrelizumab for Maintenance Treatment of Locally Advanced Non-small Cell Lung Cancer
NCT04828395 ·Status: UNKNOWN ·Phase: PHASE2
-
PD-1 Antibody Versus Best Supportive Care After Chemoradiation in Locoregionally Advanced Nasopharyngeal Carcinoma
NCT03427827 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Camrelizumab Combined With Radiotherapy and Chemotherapy for the Treatment of Recurrent or Metastatic Cervical Cancer
NCT04884906 ·Status: UNKNOWN ·Phase: PHASE2
-
Camrelizumab Combined With Local Treatment in NSCLC Patients With BM
NCT04291092 ·Status: UNKNOWN ·Phase: PHASE2
-
The Neoadjuvant Treatment of Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma
NCT04937673 ·Status: UNKNOWN ·Phase: PHASE2
-
The Efficacy of Camrelizumab Plus Stereotactic Body Radiotherapy in R/M NPC
NCT04830267 ·Status: RECRUITING ·Phase: PHASE2
-
IMRT Combined With Lobaplatin-based CCRT in Nasopharyngeal Carcinoma
NCT06688175 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE2
-
Camrelizumab After Completion of Radiotherapy for Oligometastatic Nasopharyngeal Carcinoma
NCT04221516 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of Anti-PD-1 Antibody Multimodal Combination as First-line Treatment on Time Window of Advanced Solid Tumor
NCT04282278 ·Status: UNKNOWN ·Phase: PHASE2
-
Radiation Therapy and Ammonium Tetrathiomolybdate in Treating Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer
NCT00560495 ·Status: WITHDRAWN ·Phase: PHASE1
-
Camrelizumab, Pegaspargase and Apatinib With Radiation Therapy for Stage IE/IIE ENKTL
NCT04366128 ·Status: UNKNOWN ·Phase: NA
-
Iparomlimab and Tuvonralimab Combined With SFRT and Definitive Chemoradiotherapy in Locoregionally Advanced Bulky HNSCC
NCT07041788 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Donafenib Combined With Anti-PD-1 Antibody for Neoadjuvant Therapy in Locally Advanced Thyroid Cancer
NCT06787911 ·Status: RECRUITING ·Phase: PHASE2