Radiation Therapy and Ammonium Tetrathiomolybdate in Treating Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer
NCT00560495 · Status: WITHDRAWN · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2022-10-03
Summary
RATIONALE: Ammonium tetrathiomolybdate may stop the growth of non-small cell lung cancer by blocking blood flow to the tumor. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving ammonium tetrathiomolybdate together with radiation therapy may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects of giving radiation therapy together with ammonium tetrathiomolybdate in treating patients with stage I, stage II, or stage III non-small cell lung cancer.
Conditions
Interventions
- DRUG
-
ammonium tetrathiomolybdate
4 times daily for up to 3 weeks
- OTHER
-
immunoenzyme technique
- OTHER
-
laboratory biomarker analysis
- RADIATION
-
Tc 99m sestamibi
- RADIATION
-
radiation therapy
once daily, 5 days a week, for 6-7 weeks
Sponsors & Collaborators
-
Roswell Park Cancer Institute
lead OTHER
Principal Investigators
-
Mohammad K. Khan, MD, PhD · Roswell Park Cancer Institute
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-05-31
- Primary Completion
- 2008-07-31
- Completion
- 2008-07-31
Countries
- United States
Study Locations
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