PD-1 Inhibitor and Anlotinib Combined With Multimodal Radiotherapy in Recurrent or Metastatic Anaplastic Thyroid Cancer
NCT05659186 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2022-12-21
Summary
The purpose of this study is to evaluate the efficacy and safety of PD-1 inhibitor and anlotinib combined with multimodal radiotherapy for the second-line treatment of recurrent or metastatic anaplastic thyroid cancer.
Conditions
Interventions
- DRUG
-
Tislelizumab
200mg IV Q3W
- DRUG
-
12mg PO QD
- RADIATION
-
Radiotherapy
Multimodal Radiotherapy
Sponsors & Collaborators
-
West China Hospital
lead OTHER
Principal Investigators
-
Xingchen Peng, Professor · West China Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-12-30
- Primary Completion
- 2024-12-30
- Completion
- 2025-12-30
Countries
- China
Study Locations
More Related Trials
-
SBRT Combined With Chemotherapy and Tislelizumab in Metastatic NPC
NCT05652192 ·Status: RECRUITING ·Phase: PHASE2
-
Study of Anlotinib With Chemoradiation for Patients With Locally Advanced Nasopharyngeal Carcinoma
NCT05232552 ·Status: UNKNOWN ·Phase: PHASE2
-
Study to Evaluate Safety and Efficacy of TJ107 Combine With PD-1 in Patients With Solid Tumors
NCT05145907 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Anrotinib and Tirelizumab in First-line Treatment of RM-NPC
NCT05981157 ·Status: RECRUITING ·Phase: PHASE2
-
A Clinical Study of TQB2450 Injection Combined With Chemotherapy or Anlotinib Hydrochloride Capsule in the Treatment of Non Small Cell Lung Cancer
NCT05913089 ·Status: RECRUITING ·Phase: PHASE2
-
Radiotherapy With Tislelizumab in Patients With Recurrent Head & Neck Cancer
NCT05595590 ·Status: RECRUITING ·Phase: PHASE2
-
Study of Anlotinib in Patients With Advanced Medullary Thyroid Carcinoma
NCT05830500 ·Status: RECRUITING ·Phase: PHASE4
-
Toripalimab and Anlotinib Combination Treatment in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma After Failure of at Least One Line of Platinum-Based Chemotherapy (TORAL)
NCT04996758 ·Status: COMPLETED ·Phase: PHASE2
-
Radiotherapy Combined With Thymosin for Metastatic NSCLC Patients Who Showed Stable Disease After First Line TKI Therapy
NCT02787447 ·Status: UNKNOWN ·Phase: PHASE2
-
The Efficacy and Safety of Sintilimab in Combination With Multimodal Radiotherapy in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma
NCT04917770 ·Status: UNKNOWN ·Phase: PHASE2
-
Neoadjuvant Radiotherapy Combined With Toripalimab for Locally Advanced Head and Neck Squamous Cell Carcinoma
NCT05861557 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of ST-1898 in Locally Advanced or Metastatic Radioiodine-Refractory Differentiated Thyroid Cancer
NCT06359847 ·Status: RECRUITING ·Phase: PHASE2
-
A Clinical Study of 9MW2821 (and PD-1 Inhibitor) in Locally Advanced or Metastatic Triple-Negative Breast Cancer
NCT06492005 ·Status: RECRUITING ·Phase: PHASE2
-
PD-1 Inhibitors Plus Chemoradiotherapy for Metastatic Nasopharyngeal Carcinoma: an Open-label Single-arm, Phase II Trial
NCT05520814 ·Status: UNKNOWN ·Phase: PHASE2
-
The Efficacy and Safety of Nanoparticle Albumin-bound (NAB)-Paclitaxel Plus Cisolation Versus CEP (Cisplatin, Epirubicin,Cyclophosphamide) in Induction Therapy for Thymoma: a Study for a Single-center Prospective Phase II Randomized Controlled Train.
NCT05816694 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
TQB2450 Injection Combined With Chemotherapy Followed by Sequential Combination With Anlotinib Hydrochloride Capsule for First-line Treatment of Advanced Squamous Non-small Cell Lung Cancer.
NCT05718167 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Phase II Trial of Pembrolizumab in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer
NCT05119296 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of Anlotinib in Patients With Medullary Thyroid Carcinoma(ALTER01031)
NCT02586350 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Concurrent Chemoradiotherapy Combination With Anlotinib for Unresectable Stage III NSCLC Patients
NCT03672136 ·Status: UNKNOWN ·Phase: PHASE2
-
Penpulimab Combined With GP ± Anlotinib as Neoadjuvant Therapy in Locoregionally Advanced Nasopharyngeal Carcinoma
NCT05193617 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Immunotherapy and Chemotherapy in Unresectable Recurrent Loco-regionally Advanced Nasopharyngeal Carcinoma
NCT04921995 ·Status: UNKNOWN ·Phase: PHASE2
-
Anti-PD1 Monoclonal Antibody Combined With Nimotuzumab and Capecitabine in Patients With First-line Platinum-resistant Recurrent/Metastatic Nasopharyngeal Carcinoma
NCT06259721 ·Status: RECRUITING ·Phase: PHASE2
-
A Phase II Study of CRT Combined With QL1706 in ESCC Patients
NCT05490719 ·Status: RECRUITING ·Phase: PHASE2
-
Multiple Target Kinase Inhibitor and Anti-Programmed Death-1 Antibody in Patients With Advanced Thyroid Cancer
NCT04521348 ·Status: COMPLETED ·Phase: PHASE2
-
Nivolumab Plus Lenvatinib Against Anaplastic Thyroid Cancer (NAVIGATION)
NCT05696548 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2