RD13-01 for Patients With r/r CD7+ T/NK Cell Hematologic Malignancies
NCT04538599 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2022-01-25
Summary
This study is designed to explore the safety of RD13-01 for patients with CD7+ relapsed and/or refractory T/NK-cell hematologic malignancies. And to evaluate the efficacy and pharmacokinetics of RD13-01 in patients.
Conditions
Interventions
- DRUG
-
RD13-01 cell infusion
Universal CAR-T cells targeting CD7
Sponsors & Collaborators
-
He Huang
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 3 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-09-10
- Primary Completion
- 2021-02-17
- Completion
- 2021-11-30
Countries
- China
Study Locations
More Related Trials
-
Research Development(RD)13-02 Chimeric Antigen Receptor(CAR) -T Cell Injection for Patients With r/r Cluster Of Differentiation 7(CD7)+ T-Acute Lymphoblastic Leukemia(ALL)/T-Lymphoblastic Lymphoma(LBL) /Acute Myelogenous Leukemia(AML)
NCT05907603 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
CD7-CART in the Treatment of r / r CD7 Positive Hemolymph System Malignancies on Increasing Dose and Open Label Study
NCT04480788 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of CT-RD06 Cell Injection in Patients With Relapsed or Refractory CD19+ B-cell Hematological Malignancy
NCT04226989 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Clinical Study of the Efficacy of CD19-CAR-DNT Cells in the Treatment of Relapsed/Refractory B-cell NHL
NCT05453669 ·Status: UNKNOWN ·Phase: PHASE1
-
CD70 Targeted CAR-T Cells in CD70 Positive Relapsed/Refractory Lymphoma
NCT05948033 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
CD7 CAR-T Cells for Patients With R/R CD7+ NK/T Cell Lymphoma,T-lymphoblastic Lymphoma and Acute Lymphocytic Leukemia
NCT04004637 ·Status: UNKNOWN ·Phase: PHASE1
-
Human CD19-CD22 Targeted T Cells Injection for Refractory/Relapsed Central Nervous System Leukemia/Lymphoma Patients
NCT05651178 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
SENL101 Autologous T Cell Injection in Adults With Relapsed or Refractory CD7+ Hematolymphoid Malignancies
NCT05398614 ·Status: UNKNOWN ·Phase: PHASE1
-
CD7 CAR T-cell for R/R CD7+ T Cell Lymphoma
NCT05059912 ·Status: UNKNOWN ·Phase: PHASE2
-
CD7 CAR-T for Patients With r/r CD7+ Hematologic Malignancies
NCT05454241 ·Status: COMPLETED ·Phase: PHASE2
-
Anti-CD5 CAR T Cells for Relapsed/Refractory T Cell Malignancies
NCT04594135 ·Status: UNKNOWN ·Phase: PHASE1
-
CD7 CAR-T Cells in T-cell Lymphoma/Leukemia
NCT05620680 ·Status: RECRUITING ·Phase: NA
-
Early Clinical Study of JY306 Universal NK Cell Injection in the Treatment of Adult Relapsed or Refractory CD70+ Malignant Hematologic Tumors
NCT06837389 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
CAR-NK Targeted CD19 for r/r B-cell Malignancies
NCT05645601 ·Status: UNKNOWN ·Phase: PHASE1
-
CD19 Targeted Chimeric Antigen Receptor T Cells for B Cell Lymphoma
NCT03118180 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Safety and Efficacy Evaluation of Next-generation CD19-UCART
NCT05381181 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Safety, Efficacy and Pharmacokinetics of XKDCT023 in DLBCL
NCT05269914 ·Status: UNKNOWN ·Phase: NA
-
Clinical Trial to Evaluate CD19 CAR T (CT032) in Patients With Relapsed and/or Refractory Non-Hodgkin's B Cell Lymphoma
NCT03994913 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of GNC-035 in Relapsed or Refractory Non-Hodgkin 's Lymphoma and Other Hematological Malignancies
NCT06066203 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of CD19/22 CART Cells Combined With PD-1 Inhibitor in Relapsed/Refractory B-cell Lymphoma
NCT04539444 ·Status: UNKNOWN ·Phase: PHASE2
-
Immunotherapy With CD19 CAR T-cells for B-Cell Lymphoma, ALL and CLL
NCT02546739 ·Status: UNKNOWN ·Phase: PHASE1
-
CD19-CART in the Treatment of R/R CD19 Positive Non-Hodgkin's Lymphoma
NCT04237428 ·Status: UNKNOWN ·Phase: NA
-
Study of Anti-CD19 iCAR NK Cells in Relapsed and Refractory B Cell Lymphoma
NCT03824951 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Clinical Study of Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of Relapsed/Refractory Non-Hodgkin Lymphoma
NCT05420493 ·Status: RECRUITING ·Phase: PHASE1
-
Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART133
NCT02541370 ·Status: COMPLETED ·Phase: PHASE1/PHASE2