Study of Anti-CD19 iCAR NK Cells in Relapsed and Refractory B Cell Lymphoma
NCT03824951 · Status: UNKNOWN · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2019-01-31
Summary
This is a single-centre, single-arm and open-label study to investigate the safety and efficacy of anti CD19 iCAR NK cells in patients with relapsed refractory B cell lymphoma.
Conditions
- Refractory B-Cell Lymphoma
Interventions
- BIOLOGICAL
-
Anti-CD19 iCAR NK Cells
Anti-CD19 iCAR NK Cells injection
Sponsors & Collaborators
-
Peking University Cancer Hospital & Institute
collaborator OTHER -
Allife Medical Science and Technology Co., Ltd.
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-02-01
- Primary Completion
- 2020-01-01
- Completion
- 2021-01-01
More Related Trials
-
CAR-T Treatment for Relapse / Refractory Type Safety and Effectiveness of Lymphoma
NCT03488160 ·Status: UNKNOWN ·Phase: NA
-
Study of Anti-CD22 CAR NK Cells in Relapsed and Refractory B Cell Lymphoma
NCT03692767 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
PD1-CD19-CART in Patients With r/r B-cell Lymphoma
NCT04213469 ·Status: COMPLETED ·Phase: NA
-
CD19-targeting CAR T Cells for B Cell Lymphoma
NCT02547948 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
L218CAR19 in Patients With Relapsed/Refractory B-cell Lymphoma
NCT06478381 ·Status: RECRUITING ·Phase: PHASE1
-
Targeting CD19 and CD22 CAR-T Cells Immunotherapy in Patients With Relapsed or Refractory B Cell Lymphoma
NCT04715217 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Safety of Autologous Humanized Anti-CD19 and Anti-CD20 Dual Specific CAR-T Cells in Adult Patients With Diffuse Large B-cell Lymphoma
NCT04215016 ·Status: UNKNOWN ·Phase: PHASE1
-
Clinical Trial to Evaluate CD19 CAR T (CT032) in Patients With Relapsed and/or Refractory Non-Hodgkin's B Cell Lymphoma
NCT03994913 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
CART-19 Cells for R/R B-cell Lymphoma
NCT03391726 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Safety and Efficiency Study of CD19-PD1-CART Cell in Relapsed/Refractory B Cell Lymphoma
NCT04163302 ·Status: UNKNOWN ·Phase: PHASE2
-
Exploratory Clinical Study of CD19-targeted CAR-T and CAR-DC in the Treatment of Relapsed and Refractory B-cell Lymphoma
NCT05585996 ·Status: RECRUITING ·Phase: PHASE1
-
Cytoplasmic Activated PD-1 CAR T Cells in Refractory/Relapsed B Cell Lymphoma
NCT03540303 ·Status: UNKNOWN ·Phase: PHASE1
-
Safety and Clinical Activity of ThisCART19 in Patients With r/r Non-Hodgkin's B Cell Lymphoma
NCT05106907 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of CD19/22 CART Cells Combined With PD-1 Inhibitor in Relapsed/Refractory B-cell Lymphoma
NCT04539444 ·Status: UNKNOWN ·Phase: PHASE2
-
Autologous CD19 CAR T Cells in Relapsed or Refractory B-cell Lymphoma
NCT02842138 ·Status: UNKNOWN ·Phase: PHASE1
-
Anti-CD5 CAR T Cells for Relapsed/Refractory T Cell Malignancies
NCT04594135 ·Status: UNKNOWN ·Phase: PHASE1
-
The Study of Anti-CD19 CAR NK Cells in the Treatment of Relapsed/Refractory Diffuse Large B Cell Lymphoma
NCT05673447 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
CD19 CART Cells for Patients With Relapse and Refractory CD19+ B-cell Lymphoma.
NCT03146533 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
The Safety and Efficacy of CART-19 Cells in Relapse and Refractory Patients With CD19+ B-cell Lymphoma
NCT03101709 ·Status: UNKNOWN ·Phase: PHASE1
-
CD19/20 Bispecific Nanobody-derived CAR-T Cells in B Cell Lymphoma
NCT03881761 ·Status: UNKNOWN ·Phase: PHASE1
-
Study of A-319 in Patients With Relapsed or Refractory B-cell Lymphoma
NCT04056975 ·Status: UNKNOWN ·Phase: PHASE1
-
Clinical Follow-up Study of CD19 CAR-T Expressing IL7 and CCL19 for Relapsed or Refractory B Cell Lymphoma
NCT04833504 ·Status: COMPLETED
-
CD19 CARvac T Cells for Patients With Relapsed / Refractory B Cell Malignancies
NCT04156243 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Clinical Research of CD19 Targeted CAR-T Cell in Relapsed/Refractory B Cell Lymphoma
NCT06180174 ·Status: RECRUITING ·Phase: PHASE1
-
Safety and Efficacy of Sequential CD19 and CD22 Targeted CAR-T Therapy for Relapsed/Refractory B Cell Lymphoma
NCT05651100 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2