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Association of Oral Lichen Planus and Thyroid Disease

NCT04523077 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2020-08-25

No results posted yet for this study

Summary

Thyroid disease is a common endocrine disorder. Oral lichen planus (OLP) is a chronic autoimmune disease that occurs on the oral mucosa in 1-2% of the general population.The purpose of this study was to determine whether there is an association between thyroid disease and oral planus lichen in the population of our patients. In the last few years, a couple of studies have been published in the world literature that have studied the possible association of these diagnoses in different populations. Most of the results showed a higher prevalence of thyroid disease in the population of lichen patients, compared with patients without lichen, although some results are contradictory. Some authors believe that the onset of OLP precedes thyroid dysfunction. In the population of Croatian patients with lichen, no research has been done to study the possible connection between these two diseases. The obtained results could help clarify whether there is a connection between these two diagnoses in the population of our lichen patients and enable earlier detection of patients with thyroid hypofunction.

Conditions

  • Oral Lichen Planus
  • Thyroid Diseases

Interventions

DIAGNOSTIC_TEST

determination of thyroid hormones and antibodies

TSH, fT3, fT4, anti-TPO and anti-Tg were determined from blood sample

Sponsors & Collaborators

  • University of Zagreb

    lead OTHER

Eligibility

Min Age
35 Years
Max Age
70 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-01-01
Primary Completion
2020-04-30
Completion
2020-04-30

Countries

  • Croatia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04523077 on ClinicalTrials.gov