MedTrace Logo

Blood Volume Assessment in COVID-19 and Bacterial Sepsis

NCT04517695 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 39

Last updated 2023-09-21

No results posted yet for this study

Summary

In patients with SARS-CoV-2 or bacterial infection admitted to the intensive care unit (ICU), the state of the intravascular volume, the characteristics of the blood volume components, and the development of a vascular leak is currently unknown. The relationship of these parameters with parameters of cardiac performance, lung edema and sublingual microcirculatory perfusion parameters have never been studied.

Conditions

Interventions

DEVICE

BVA-100

The BVA-100 is a software package designed to calculate human blood volume using the method of tracer dilution. It uses tagged serum albumin.

DEVICE

Transpulmonary Thermodilution (TPTD)

TPTD consists of placing a thermistor-equipped catheter in a central artery (usually the femoral or axillary artery) and injecting cold saline solution into a central vein through a central venous catheter.

DEVICE

Sublingual Microcirculation

With incident dark field imaging, the CytoCam device can record digital image sequences using a handheld camera. In the current study the camera will be used to non-invasively record images of the sublingual microcirculation.

Sponsors & Collaborators

Principal Investigators

  • Jan Bakker, MD, PhD · NYU Langone Health

Eligibility

Min Age
18 Years
Max Age
95 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-08-01
Primary Completion
2023-04-09
Completion
2023-04-09
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04517695 on ClinicalTrials.gov