MedTrace Logo

High Flow Nasal Cannula With Noninvasive Ventilation

NCT04507425 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 6

Last updated 2023-11-21

No results posted yet for this study

Summary

This is a prospective, randomized, unblinded trial of trauma patients in the ICU who are identified as being at a high risk to develop acute respiratory failure.

We hope that this study will help the study team to identify how best to use a more aggressive respiratory treatment strategy in a high risk trauma population (thoracic trauma or trauma patients requiring thoracic surgery, spine surgery, or open abdominal procedures) to try and decrease the need for intubation with mechanical ventilation.

Conditions

  • Acute Respiratory Failure

Interventions

OTHER

Standard of Care - Nasal Cannula

Standard of care. Flexible tube to provide extra oxygen when patients need a little help, but are not in respiratory distress.

OTHER

High-flow nasal cannula

Same as nasal cannula, except the oxygen is heated or humidified and the flow is stronger, pushing air into the lungs to help keep the airway open.

OTHER

HFNC plus non-invasive ventilation

This method uses HFNC as described above and adds noninvasive ventilation which is similar to CPAP machine and uses a mask rather than having to intubate (putting a tube down your throat to keep your airway from collapsing).

Sponsors & Collaborators

  • University of Oklahoma

    lead OTHER

Principal Investigators

  • Celia Y Quang, MD · University of Oklahoma

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-09-01
Primary Completion
2023-07-10
Completion
2023-07-10

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04507425 on ClinicalTrials.gov