Inclusive Invasive Physiological Assessment in Angina Syndromes Registry

Summary

This study evaluates the prognostic value and potential therapeutic impact of combined pressure and flow measurements in the evaluation of epicardial coronary stenosis and microvascular function.

Conditions

• Coronary Artery Disease
• Microvascular Coronary Artery Disease

Interventions

DIAGNOSTIC_TEST

Resting distal coronary to aortic pressure ratio, Fractional flow reserve, Coronary Flow Reserve, Microvascular resistance

Calculation of the resting mean distal coronary to aortic pressure ratio (resting Pd/Pa), fractional flow reserve (Pd/Pa at hyperemia), Coronary flow reserve (peak flow/resting flow), microvascular resistance (Pd/flow).

Sponsors & Collaborators

• Amsterdam UMC, location VUmc

  collaborator OTHER

• Tergooi Hospital

  collaborator OTHER

• Amphia Hospital

  collaborator OTHER

• Seoul National University Hospital

  collaborator OTHER

• Samsung Medical Center

  collaborator OTHER

• Inje University

  collaborator OTHER

• Keimyung University Dongsan Medical Center

  collaborator OTHER

• Ulsan University Hospital

  collaborator OTHER

• Tsuchiura Kyodo General Hospital

  collaborator OTHER

• Hospital San Carlos, Madrid

  collaborator OTHER

• Aarhus University Hospital

  collaborator OTHER

• Catholic University of the Sacred Heart

  collaborator OTHER

• University of Cincinnati

  collaborator OTHER

• Gifu Heart Center

  collaborator OTHER

• Toda Central General Hospital

  collaborator UNKNOWN

• Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

  lead OTHER

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-06-01

Primary Completion

2021-03-25

Completion

2021-03-25

Countries

• United States
• Denmark
• Italy
• Japan
• Netherlands
• South Korea
• Spain

Study Locations