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The Association Between Central Aortic Blood Pressure Indices and Severity of Coronary Artery Disease

NCT02471768 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 623

Last updated 2015-06-17

No results posted yet for this study

Summary

Abstract

Objectives:

Primary: To study the association between central aortic blood pressure indices and coronary artery disease in patients undergoing elective angiography. Secondary: (a) To study whether any association exists between central aortic pressure indices and the incidence of major adverse cardiovascular events (MACE) in the same patients during a 6 month follow up period. (b) To study whether any association exists between the central aortic pressures and peripheral pressures.

Methods: The investigators conducted a prospective observational study in consecutive patients undergoing coronary angiography. Central and peripheral pressures were invasively recorded and coronary artery disease (CAD) classified into obstructive and non-obstructive group. CAD severity was graded using the Gensini score and subjects were divided into tertiles. Patients were followed up and the role of central aortic pressure indices in the prediction of cardiovascular events were analysed.

Conditions

Interventions

PROCEDURE

CORONARY ANGIOGRAM AND CENTRAL AORTIC WAVEFORM ANALYSIS

coronary angiogram

Sponsors & Collaborators

  • Government Medical College, Kozhikode

    lead OTHER

Principal Investigators

  • SHREETAL R NAIR · Government Medical College, Kozhikode

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-04-30
Primary Completion
2015-03-31
Completion
2015-06-30

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Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02471768 on ClinicalTrials.gov