Deep Transcranial Magnetic Stimulation for the Treatment of Treatment Resistance Schizophrenia
NCT04478032 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2021-09-14
Summary
Based on the hypothesis that low-frequency deep transcranial magnetic stimulation(dTMS) on anterior cingulate cortex (ACC) could down-regulate the glutamate level of ACC and regulate the acc-related functional network in patients with treatment resistance schizophrenia,this research plan to utilise multimodal functional magnetic imaging method(including structural MRI,resting-state functional magnetic resonance imaging and 1H-MRS) to investigate therapeutic efficacy of low-frequency deep transcranial magnetic stimulation on SZ patients symptoms,as well as to elucidate the correlation between treatment effects and glutamate level of ACC
Conditions
- Deep Transcranial Magnetic Stimulation for the Treatment of Treatment Resistance Schizophrenia
Interventions
- DEVICE
-
deep transcranial magnetic stimulation with H7 coil
low frequency(1Hz) deep transcranial magnetic stimulation on ACC .Duration:20 days.
Sponsors & Collaborators
-
Shanghai Mental Health Center
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-07-05
- Primary Completion
- 2022-12-31
- Completion
- 2022-12-30
Countries
- China
Study Locations
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