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Effects of Silica and Asbestos Fibres on the Efferocytosis Capacities of Macrophages

NCT04473742 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2022-01-04

No results posted yet for this study

Summary

Evaluation of the efferocytosis capacities of blood Monocyte Derived Macrophages (MDM) from patients with a history of asbestosis or silica exposure and comparison of these capacities with those of MDM from healthy donors.

Conditions

  • History of Exposure to Silica or Asbestosis
  • Positive Testing for ANA as a Marker of Systemic Autoimmune Diseases

Interventions

BIOLOGICAL

Blood collection

4 EDTA tubes for 24 mL blood collection

BIOLOGICAL

Blood sample

2 drying tubes for 12 mL blood collection

BIOLOGICAL

Blood sample

1 drying tube for 6 mL blood collection

Sponsors & Collaborators

  • Rennes University Hospital

    lead OTHER

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-03-31
Primary Completion
2021-12-15
Completion
2021-12-15

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04473742 on ClinicalTrials.gov