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MMP-9, TIMP-9 in Lung Imaging and Functional of COVID-19

NCT05844215 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 78

Last updated 2023-05-06

No results posted yet for this study

Summary

This study aims to determine the role of the extracellular matrix in lung abnormalities in COVID-19 patients. Anatomical abnormalities of the lungs can be observed by the presence of abnormalities on a chest x-ray that is scored using the Brixia index. The presence of COVID-19 pneumonia can impact oxygenation disorders. It is hoped that knowing the relationship between biomarkers that affect the extracellular matrix and anatomical and functional abnormalities can open up new insights into new therapeutic opportunities. The balance of MMP-9 and TIMP-1 has been studied in relation to several lung diseases other than COVID-19.

Conditions

  • Pulmonary Infection
  • COVID-19
  • Extracellular Matrix Alteration

Interventions

DIAGNOSTIC_TEST

MMP-9 and TIMP-1

Examine level of serum MMP-9 and TIMP-1

Sponsors & Collaborators

  • Universitas Airlangga

    lead OTHER

Principal Investigators

  • Muhammad Amin, Prof. · Airlangga University Faculty of Medicine: Universitas Airlangga Fakultas Kedokteran

Eligibility

Min Age
21 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-03-15
Primary Completion
2021-12-24
Completion
2022-07-20

Countries

  • Indonesia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05844215 on ClinicalTrials.gov