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The Effect of Probiotic Streptococci and pH-rising Components on the Oral Microbial Flora

NCT02677480 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2016-02-09

No results posted yet for this study

Summary

The test group consisted of eighteen subjects with hyposalivation used probiotic tablets (≥ 4/day) and gel (once a week) (streptococci, bicarbonate and carbamide) for 3 months and 9 used placebo tablets and gel. The salivary secretion rates were measured and microbial samples collected and analysed using cultivation technique twice both at baseline and at the 3-month follow up (1-2 weeks between the appointments).

Conditions

  • Hyposalivation

Interventions

DIETARY_SUPPLEMENT

Test group, probiotic tablets and gel

Effect of probiotic tablets and gel on acidogenic bacteria

DIETARY_SUPPLEMENT

Placebo group, placebo tablets and gel

Effect of placebo tablets and gel on acidogenic bacteria

Sponsors & Collaborators

  • Vinnova

    collaborator OTHER_GOV

  • Vastra Gotaland Region

    collaborator OTHER_GOV

  • Göteborg University

    lead OTHER

Principal Investigators

  • Annica Almstahl, Assoc. prof. · Goteborg University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-11-30
Primary Completion
2010-11-30
Completion
2010-11-30

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02677480 on ClinicalTrials.gov