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Pupillary Response to Incremental Tetanic Stimulations Under Propofol-remifentanil TCI

NCT04465773 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 18

Last updated 2020-07-10

No results posted yet for this study

Summary

In patients under standardized steady-state general anesthesia, 6 tetanic stimulations of incremental intensities were applied to the patients. Pupillary dilation in response to these stimulations was recorded.

Conditions

Interventions

PROCEDURE

general anesthesia for scheduled gynecological surgery

DRUG

Propofol

continuous infusion, target concentration adjusted to maintain bispectral index between 45 and 55

DRUG

Remifentanil, Ultiva®

continuous infusion, target concentration 1 ng/ml

PROCEDURE

tetanic stimulations

10-20-30-40-50-60 milliamps, 5 seconds, 100 Hertz 2 minutes between stimulations delivered via the standard neuromuscular blocking agents monitor

DEVICE

VideoAlgesiGraph

non invasive infrared camera placed in front of the left eye of the patients during the study period, connected to a laptop. No part of the device touches the eye.

Sponsors & Collaborators

  • Pr Isabelle CONSTANT

    lead OTHER

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-01-31
Primary Completion
2012-11-30
Completion
2013-07-31

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04465773 on ClinicalTrials.gov