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Influence of Depth of Anesthesia on Pupillary Reactivity to a Standardized Stimulus

NCT02595476 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2017-04-04

No results posted yet for this study

Summary

A standardized tetanic stimulation is applied to patients under propofol-remifentanil TCI, in a cross-over fashion, at two different levels of anesthesia monitored by the BIS: BIS 25 and BIS 55. Remifentanil target remains constant during the whole study period (1 ng/ml). Pupillary reflex dilation is recorded after each stimulation.

Conditions

Interventions

DRUG

Remifentanil

DRUG

propofol

DEVICE

TCI

PROCEDURE

Tetanic stimulation

DEVICE

Algiscan

Pupillometry

Sponsors & Collaborators

  • Hôpital Armand Trousseau

    lead OTHER

Principal Investigators

  • Isabelle Constant, MD, PHD · Hopital Armand Trousseau

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
10 Years
Max Age
20 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-31
Primary Completion
2016-01-31
Completion
2016-03-31

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02595476 on ClinicalTrials.gov