Study of Decidual Stromal Cells to Treat COVID-19 Respiratory Failure
NCT04451291 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 19
Last updated 2024-02-05
Summary
This is a research study to see how safe and effective decidual stromal cells are in treating patients with respiratory failure (breathing problem where not enough oxygen is passed from the lungs into the blood) caused by COVID-19.
Conditions
- COVID-19
- Acute Respiratory Distress Syndrome
Interventions
- BIOLOGICAL
-
Decidual Stromal Cells (DSC)
DSCs are involved in the immune system during pregnancy. The DSCs used in this study will come from laboratory grown allogeneic human decidual stromal cells obtained from donated placentas.
Sponsors & Collaborators
-
Oslo University Hospital
collaborator OTHER -
University Health Network, Toronto
lead OTHER
Principal Investigators
-
John Granton, M.D. · Toronto General Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-09-25
- Primary Completion
- 2023-11-07
- Completion
- 2023-11-07
Countries
- Canada
Study Locations
More Related Trials
-
Myeloid Suppressors in Inflammation
NCT01224223 ·Status: COMPLETED
-
Dendritic Cell Vaccine Study (DC/PC3) for Prostate Cancer
NCT00345293 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safe Study of Dendritic Cell (DC) Based Therapy Targeting Tumor Stem Cells in Glioblastoma
NCT00846456 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
In Vitro Functional Modulation of Monocyte-derived Dendritic Cells of Patients With Cancer by Peptides
NCT02159937 ·Status: COMPLETED
-
Phase I/II Study of Vaccination With Antigen Loaded Dendritic Cells (DCs) in Hormone-Refractory Prostate Cancer
NCT01897207 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Dendritic Cell Based Therapy of Metastatic Breast Cancer
NCT00197925 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
A Study Evaluating Vaccination of Prostate Cancer Patients With Self Dendritic Cells Expressing MUC1
NCT00852007 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Radiation Therapy and Intratumoral Autologous Dendritic Cells in Soft Tissue Sarcomas (STS)
NCT01347034 ·Status: COMPLETED ·Phase: PHASE2
-
Study of HER2 Directed Dendritic Cell (DC1) Vaccine + Weekly Paclitaxel, Trastuzumab & Pertuzumab
NCT05325632 ·Status: RECRUITING ·Phase: PHASE2
-
Trial of Vaccine Therapy With mRNA- Transfected Dendritic Cells in Patients With Androgen Resistant Metastatic Prostate Cancer
NCT01278914 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
The Role of Cxcr4Hi neutrOPhils in InflueNza
NCT06254313 ·Status: RECRUITING
-
A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-DFU-302 Clinical Trial
NCT06141811 ·Status: RECRUITING
-
Dendritic Cell Based Therapy of Malignant Melanoma
NCT00197912 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Dendritic Cells for Immunotherapy of Metastatic Endometrial Cancer Patients
NCT04212377 ·Status: COMPLETED ·Phase: PHASE2
-
A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-BI-101 Clinical Trial
NCT03183622 ·Status: COMPLETED
-
Cytotoxicity Induced by Tumor Lysate Pulsed Dendritic Cells Against Autologous Hepatocellular Carcinoma Cells
NCT00327496 ·Status: UNKNOWN ·Phase: NA
-
Autologous Dendritic Cells Pulsed With Autologous Apoptotic Tumor Cells Administered to Patients With Brain Tumors
NCT00893945 ·Status: COMPLETED ·Phase: PHASE1
-
A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-DFU-101 Clinical Trial
NCT03183726 ·Status: COMPLETED
-
Autologous Decidual-like Natural Killer Cells Therapy for Reproductive Failure
NCT07230574 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Administration of Autologous Dendritic Cells (DCs) Infected With an Adenovirus Expressing Her-2
NCT00197522 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of DC-CIK to Treat Hepatocellular Carcinoma
NCT01821482 ·Status: UNKNOWN ·Phase: PHASE2
-
A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)
NCT05809752 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Dendritic Cells in Lung Cancer
NCT00442754 ·Status: COMPLETED ·Phase: PHASE2
-
A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-DFU-301 Clinical Trial
NCT04590703 ·Status: COMPLETED
-
AMI-DC in Patients With Anterior Wall Myocardial Infarction
NCT05554484 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2