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The Role of Cxcr4Hi neutrOPhils in InflueNza

NCT06254313 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2024-12-27

No results posted yet for this study

Summary

Influenza is still responsible for more than 650,000 deaths per year worldwide and no major improvements in patients' care has been made despite 50 years of research. Especially, there is no therapeutic strategy targeting the dysregulated host response. CXCR4-expressing neutrophils seem to be involved in the rupture of host resistance. The aim of this study is thus to compare the percentage of blood CXCR4-expressing neutrophils between influenza survivors and non-survivors.

Conditions

  • Influenza
  • Acute Respiratory Distress Syndrome

Interventions

OTHER

Additional tubes and LBA

4 Additional tubes taken when blood is drawn during treatment : EDTA tubes and 2 citrate tubes and bronchoalveolar fluid sample (LBA)

Sponsors & Collaborators

  • University Hospital, Bordeaux

    lead OTHER

Principal Investigators

  • Edouard LHOMME, Dr · Unité de Soutien Méthodologique à la Recherche clinique et épidémiologique du CHU de Bordeaux

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-31
Primary Completion
2026-12-31
Completion
2026-12-31

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06254313 on ClinicalTrials.gov